3 Butyrophilin-3a is expressed in multiple solid tumors: translational research supporting the EVICTION study with ICT01, an anti-BTN3A mAb activating Vg9Vd2 T-Cells

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NEOPLASIA Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function

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Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function.

An important aspect of tumor progression is the ability of cancer cells to escape detection and clearance by the immune system. Recent studies suggest that several tumors express soluble factors interfering with the immune response. Here, we show that semaphorin-3A (Sema-3A), a secreted member of the semaphorin family involved in axonal guidance, organogenesis, and angiogenesis, is highly expre...

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Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations

Syntaxin is one of several proteins that may be involved in the docking of synaptic vesicles, synaptic vesicle recycling, and non-synaptic membrane trafficking. Presence of syntaxin has been reported in rat auditory and vestibular end organs. In the current study, we have examined the expression of message for syntaxin 1 in hair cells of the sacculus of the rainbow trout, Oncorhynchus mykiss, w...

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Syntaxin 1 is expressed in the trout saccular hair cells: RT-PCR and immunocytochemical observations

Syntaxin is one of several proteins that may be involved in the docking of synaptic vesicles, synaptic vesicle recycling, and non-synaptic membrane trafficking. Presence of syntaxin has been reported in rat auditory and vestibular end organs. In the current study, we have examined the expression of message for syntaxin 1 in hair cells of the sacculus of the rainbow trout, Oncorhynchus mykiss, w...

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ژورنال

عنوان ژورنال: Journal for ImmunoTherapy of Cancer

سال: 2020

ISSN: 2051-1426

DOI: 10.1136/jitc-2020-sitc2020.0003